Tuberculosis: An Update

Course #54555-


Self-Assessment Questions

    1 . Evidence of tuberculosis (TB) has been found in archeological digs dating back
    A) 6,500 years.
    B) 5,500 years.
    C) 4,500 years.
    D) 3,500 years.

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    2 . What country was the last in the world without TB infection?
    A) Russia
    B) China
    C) United States
    D) New Guinea

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    3 . Within the body, TB organisms
    A) are engulfed and killed by macrophages.
    B) reside indefinitely in an active stage in the body.
    C) are walled off by macrophages in encapsulated granulomas called tubercles.
    D) replicate and gain access to lymphatic channels through the blood stream.

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    4 . The average time of exposure to someone with active TB until acquisition of infection is about
    A) two hours.
    B) two days.
    C) two weeks
    D) two months.

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    5 . During the asymptomatic phase, the only evidence of infection with TB may be
    A) dry cough and fever.
    B) chest pain and dyspnea.
    C) cervical node enlargement.
    D) skin-test reactivity to tuberculin.

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    6 . Clinical emergence of active TB occurs in what percentage of those with latent TB infection?
    A) 1% to 2%
    B) 10% to 15%
    C) 25% to 30%
    D) 80% to 90%

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    7 . The usual cause for secondary or reactivation TB is a breakdown of the patient's
    A) immune system.
    B) digestive system.
    C) circulatory system.
    D) integumentary system

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    8 . The most common early symptoms of pulmonary TB are
    A) hyperactivity.
    B) rales and rhonchi.
    C) chest pain upon inspiration.
    D) cough, malaise, and weight loss.

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    9 . Groups considered high risk for contracting TB who should be screened include HIV-infected persons, injecting drug users, and
    A) all hospital workers.
    B) emergency medical personnel.
    C) persons with healthy immune systems.
    D) residents in areas with severe air pollution.

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    10 . Foreign-born persons originating from countries with high TB prevalence should be
    A) quarantined.
    B) administered BCG vaccine.
    C) screened for possible TB infection.
    D) started on chemoprophylaxis as soon as possible.

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    11 . A negative reaction to a tuberculin skin test
    A) is <5 mm in diameter.
    B) is often a misread conversion.
    C) indicates a strong immune system.
    D) rules out TB as the source of infection.

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    12 . When teaching a patient to produce a sputum specimen, instruct him or her to
    A) drink a large glass of water before coughing.
    B) collect the specimen just before going to sleep at night.
    C) cough gently and expectorate into the sputum container.
    D) bring the specimen up from their lungs (not throat) after a deep cough.

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    13 . Nucleic acid amplification tests (NAATs) for the diagnosis of TB
    A) are not approved by the FDA.
    B) require more than one month for results.
    C) may not be used with smear-positive specimens.
    D) are able to differentiate between different species of M. tuberculosis.

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    14 . The most common site for extrapulmonary TB is the
    A) liver.
    B) skin.
    C) kidney.
    D) adrenal gland.

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    15 . Miliary tuberculosis refers to an infection affecting the
    A) skin.
    B) testes.
    C) GI tract.
    D) entire body.

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    16 . Two first-line drugs used in the treatment of drug-susceptible TB include
    A) isoniazid and rifampin.
    B) rifabutin and streptomycin.
    C) rifapentine and capreomycin.
    D) ethionamide and ethambutol.

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    17 . Chemoprophylaxis is recommended for all of the following groups of people with a positive tuberculin test of 6 mm, EXCEPT:
    A) Children older than 4 years of age
    B) Persons with known or suspected HIV infection
    C) Close contacts of persons with infectious, clinically active TB
    D) Persons who inject drugs and who are known to be HIV negative

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    18 . Bacille Calmette-Guérin (BCG) vaccine
    A) is used regularly in the United States.
    B) does not have any effect on the tuberculin skin test.
    C) is one of the most widely used vaccines in the world.
    D) is internationally regulated to ensure that only one strain is used.

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    19 . Prophylactic treatment for children of patients infected with TB is
    A) contraindicated.
    B) highly recommended.
    C) usually recommended only if the child is HIV positive.
    D) recommended only if close monitoring of liver function is done.

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    20 . It is important for the healthcare professional to explain to the patient with TB and his/her caregiver
    A) the signs and symptoms of drug toxicity.
    B) instructions outlining which medications to take and how often.
    C) information about where financial assistance and free medications can be found in the community.
    D) All of the above

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