1. Gukasyan N, Davis AK, Barrett FS, et al. Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: prospective 12-month follow-up. J Psychopharmacol. 2022;36(2):151-158.

2. Gander K. Why Don't Antidepressants Work for Some People? Scientists Offer New Answer. Available at https://www.newsweek.com/why-dont-antidepressants-work-some-people-scientists-offer-new-answer-1372051. Last accessed June 13, 2022.

3. Huizen J. What To Know About Prozac Withdrawal Symptoms. Available at https://www.medicalnewstoday.com/articles/prozac-withdrawal. Last accessed June 13, 2022.

4. Ly C, Greb AC, Cameron LP, et al. Psychedelics promote structural and functional neural plasticity. Cell Rep. 2018;23(11):3170-3182.

5. Hesselgrave N, Troppoli TA, Wulff AB, Cole AB, Thompson SM. Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice. Proc Natl Acad Sci U S A. 2021;118(17):e2022489118.

6. Grinspoon DH, Grinspoon L, Bakalar JB. Psychedelic Drugs Reconsidered. New York, NY: Basic Books; 1979.

7. Lucas R. FBI Data Shows an Unprecedented Spike in Murders Nationwide in 2020. Available at https://www.npr.org/2021/09/27/1040904770/fbi-data-murder-increase-2020. Last accessed June 13, 2022.

8. Gold M. Medicinal marijuana, stress, anxiety, and depression: primum non nocere. Mo Med. 2020;117(5):406-411.

9. American Association of Suicidology. Facts and Statistics. Available at https://suicidology.org/facts-and-statistics. Last accessed June 15, 2022.

10. National Institute of Mental Health. Suicide. Available at https://www.nimh.nih.gov/health/statistics/suicide. Last accessed June 21, 2022.

11. National Institute of Mental Health. Major Depression. Available at https://www.nimh.nih.gov/health/statistics/major-depression. Last accessed June 21, 2022.

12. Substance Abuse and Mental Health Services Administration. Key Substance Use and Mental Health Indicators in the United States: Results from the 2020 National Survey on Drug Use and Health. Available at https://www.samhsa.gov/data/report/2020-annual-national-report. Last accessed June 21, 2022.

13. PR Newswire. Psychedelic Drugs Market Size is Projected to Reach $10.75 Billion by 2027. Available at https://www.prnewswire.com/news-releases/psychedelic-drugs-market-size-is-projected-to-reach-10-75-billion-by-2027--301273405.html. Last accessed June 13, 2022.

14. Curtin SC, Hedegaard H, Ahmad FB. Provisional numbers and rates of suicide by month and demographic characteristics: United States, 2020. Natl Vital Stat Rep. 2021;16.

15. Psych. The Psychedelics as Medicine Report: Third Edition. Available at https://psych.global/report. Last accessed June 14, 2022.

16. National Conference of State Legislatures. State Medical Cannabis Laws. Available at https:www.ncsl.org/research/health/state-medical-marijuana-laws.aspx. Last accessed June 13, 2022.

17. Yakowicz W. U.S. House of Representatives Passes Federal Cannabis Legalization Bill MORE Act. Available at https://www.forbes.com/sites/willyakowicz/2022/04/01/us-house-of-representatives-pass-federal-cannabis-legalization-bill-more-act/?sh=4bfd858766d7. Last accessed June 13, 2022.

18. Hartman M. Cannabis Overview. Available at https://www.ncsl.org/research/civil-and-criminal-justice/marijuana-overview.aspx. Last accessed June 14, 2022.

19. Gilman IY, Shields KI. At Harvard, Psychedelic Drugs' Tentative Renaissance. Available at https://www.thecrimson.com/article/2022/2/19/psychedelics-tentative-renaissance/. Last accessed June 14, 2022.

20. Feuer W. Oregon Becomes First State to Legalize Magic Mushrooms as More States Ease Drug Laws in "Psychedelic Renaissance." Available at https://www.cnbc.com/2020/11/04/oregon-becomes-first-state-to-legalize-magic-mushrooms-as-more-states-ease-drug-laws.html. Last accessed June 14, 2022.

21. Lowe H, Toyang N, Steele B, et al. The therapeutic potential of psilocybin. Molecules. 2021;26(10):2948.

22. Yale School of Medicine. Grant Supports Development of Training for Psychiatrists in Psychedelic Medicine. Available at https://medicine.yale.edu/news-article/grant-supports-development-of-training-for-psychiatrists-in-psychedelic-medicine. Last accessed June 21, 2022.

23. U.S. Drug Enforcement Administration. List of Controlled Substances. Available at https://www.deadiversion.usdoj.gov/schedules. Last accessed June 21, 2022.

24. Breitbart W, Rosenfeld B, Pessin H, et al. Depression, hopelessness, and desire for hastened death in terminally ill patients with cancer. JAMA. 2000;284(22):2907-2911.

25. Grob CS, Danforth AL, Chopra GS, et al. Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Arch Gen Psychiatry. 2011;68(1):71-78.

26. Jones G, Ricard JA, Lipson J, Nock MK. Associations between classic psychedelics and opioid use disorder in a nationally representative U.S. adult sample. Sci Rep. 2022;12(1):4099.

27. Pisano VD, Putnam NP, Kramer HM, Franciotti KJ, Halpern JH, Holden SC. The association of psychedelic use and opioid use disorders among illicit users in the United States. J Psychopharmacol. 2017;31(5):606-613.

28. Rucker JJH, Iliff J, Nutt DJ. Psychiatry and the psychedelic drugs: past, present and future. Neuropharmacology. 2018;142:200-218.

29. Hoffman A. LSD My Problem Child: Reflections on Sacred Drugs, Mysticism, and Science. 4th ed. Santa Cruz, CA: Multidisciplinary Association for Psychedelic Studies; 2017.

30. Belouin SJ, Henningfield JE. Psychedelics: where we are now, why we got here, what we must do. Neuropharmacology. 2018;142:7-19.

31. Bonson KR. Regulation of human research with LSD in the United States (1949–1987). Psychopharmacology (Berl). 2018;235(2):591-604.

32. Johnson MW, Richards WA, Griffiths RR. Human hallucinogen research: guidelines for safety. J Psychopharmacol. 2008;22(6):603-620.

33. Studerus E, Gamma A, Kometer M, Vollenweider FX. Prediction of psilocybin response in healthy volunteers. PLoS One. 2012;7(2):e30800.

34. Shapiro M. Inside the Johns Hopkins Psilocybin Playlist. Available at https://www.hopkinsmedicine.org/news/articles/inside-the-johns-hopkins-psilocybin-playlist. Last accessed June 14, 2022.

35. Schenberg EE. Psychedelic-assisted psychotherapy: a paradigm shift in psychiatric research and development. Front Pharmacol. 2018;9:733.

36. Whitehurst L. "Magic Mushrooms" for Therapy? Veterans Help Sway Conservatives. Available at https://www.sltrib.com/news/2022/04/17/magic-mushrooms-therapy. Last accessed June 14, 2022.

37. Dinis-Oliveira RJ, Pereira CL, da Silva DD. Pharmacokinetic and pharmacodynamic aspects of peyote and mescaline: clinical and forensic repercussions. Curr Mol Pharmacol. 2019;12(3):184-194.

38. Meinhardt MW, Pfarr S, Fouquet G, et al. Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism. Sci Adv. 2021;7(47):eabh2399.

39. Rucker JJ, Marwood L, Ajantaival RLJ, et al. The effects of psilocybin on cognitive and emotional functions in healthy participants: results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation.J Psychopharmacol. 2022;36(1):114-125.

40. Zeiss R, Gahr M, Graf H. Rediscovering psilocybin as an antidepressive treatment strategy. Pharmaceuticals (Basel). 2021;14(10):985.

41. Carhart-Harris RL, Bolstridge M, Day CMJ, et al. Psilocybin with psychological support for treatment-resistant depression: six-month follow-up. Psychopharmacology (Berl). 2018;235(2):399-408.

42. Carhart-Harris R, Giribaldi B, Watts R, et al. Trial of psilocybin versus escitalopram for depression. N Engl J Med. 2021;384(15):1402-1411.

43. Daws RE, Timmermann C, Giribaldi B, et al. Increased global integration in the brain after psilocybin therapy for depression.Nat Med. 2022;28(4):844-851.

44. Domino EF. Taming the ketamine tiger. Anesthesiology. 2010;113(3):678-684.

45. Sassano-Higgins S, Baron D, Juarez G, Esmaili N, Gold M. A review of ketamine abuse and diversion. Depress Anxiety. 2016;33(8):718-27.

46. Cleveland Clinic. Date rape drugs: what parents should know. Cleve Clin J Med. 2001;68(6):551-552.

47. Carboni E, Carta AR, Carboni E, Novelli A. Repurposing ketamine in depression and related disorders: can this enigmatic drug achieve success? Front Neurosci. 2021;15:657714.

48. Aust S, Gärtner M, Basso L, et al. Anxiety during ketamine infusions is associated with negative treatment responses in major depressive disorder. Eur Neuropsychopharmacol. 2019;29(4):529-538.

49. Feder A, Costi S, Rutter SB, et al. A randomized controlled trial of repeated ketamine administration for chronic posttraumatic stress disorder. Am J Psychiatry. 2021;178(2):193-202.

50. Abbar M, Demattei C, El-Hage W, et al. Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo-controlled trial. BMJ. 2022;376:e067194.

51. National Institute on Drug Abuse. MDMA (Ecstasy) Abuse Research Report: Introduction. Available at https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/Introduction. Last accessed June 14, 2022.

52. Vermetten E, Yehuda R. MDMA-assisted psychotherapy for posttraumatic stress disorder: a promising novel approach to treatment. Neuropsychopharmacology. 2020;45(1):231-232.

53. National Institute on Drug Abuse. MDMA (Ecstasy) Abuse Research Report: What is the History of MDMA? Available at https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-is-the-history-of-mdma. Last accessed June 14, 2022.

54. Mithoefer MC. A Manual for MDMA-Assisted Psychotherapy in the Treatment of Posttraumatic Stress Disorder. Version 8.1. Available at https://maps.org/2014/01/27/a-manual-for-mdma-assisted-therapy-in-the-treatment-of-ptsd/. Last accessed June 14, 2022.

55. Mithoefer MC, Feduccia AA, Jerome L, et al. MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials. Psychopharmacology (Berl). 2019;236(9): 2735-2745.

56. Mitchell JM, Bogenschutz M, Lilienstein A, et al. MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nat Med. 2021;27:1025-1033.

57. Ponte L, Jerome L, Hamilton S, et al. Sleep quality improvements after MDMA-assisted psychotherapy for the treatment of posttraumatic stress disorder. J Trauma Stress. 2021;34(4):851-863.

58. Jerome L, Feduccia AA, Wang JB, et al. Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials. Psychopharmacology (Berl). 2020;237(8):2485-2497.

59. Centers for Disease Control and Prevention. Death Rate Maps and Graphs. Available at https://www.cdc.gov/drugoverdose/deaths/index.html. Last accessed June 14, 2022.

60. Hevesi D. Howard Lotsof Dies at 66; Saw Drug Cure in a Plant. Available at https://www.nytimes.com/2010/02/17/us/17lotsof.html. Last accessed June 14, 2022.

61. Noller GE, Frampton CM, Yazar-Klosinski B. Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study. Am J Drug Alcohol Abuse. 2018;44(1):37-46.

62. Wilson C, Millar T, Matieschyn Z. Novel treatment of opioid use disorder using ibogaine and iboga in two adults. J Psychedelic Stud. 2021;4(3):149-155.

63. Mash DC, Duque L, Page B, Allen-Ferdinand K. Ibogaine detoxification transitions opioid and cocaine abusers between dependence and abstinence: clinical observations and treatment outcomes. Front Pharmacol. 2018;9:529.

64. Oesterle TS, Thusius NJ, Rummans TA, Gold MS. Medication-assisted treatment for opioid-use disorder. Mayo Clin Proc. 2019;94(10):2072-2086.

65. Partnership to End Addiction. Six States Ban Kratom Over Concerns About Addiction Potential. Available at https://drugfree.org/drug-and-alcohol-news/six-states-ban-kratom-concerns-addiction-potential. Last accessed June 15, 2022.

66. Author interview with Christopher McCurdy on March 6, 2022.

67. Ramanathan S, McCurdy CR. Kratom (Mitragyna speciosa): worldwide issues. Curr Opin Psychiatry. 2020;33(4):312-318.

68. Prozialeck WC, Edwards JR, Lamar PC, et al. Evaluation of the mitragynine content, levels of toxic metals and the presence of microbes in kratom products purchased in the western suburbs of Chicago. Int J Environ Res Public Health. 2020;17(15):5512.

69. Centers for Disease Control and Prevention. Multistate Outbreak of Salmonella Infections Linked to Kratom (Final Update). Available at https://www.cdc.gov/salmonella/kratom-02-18/index.html. Last accessed June 17, 2022.

70. McGill University. Press Release: LSD, a Future Anti-Anxiety Pill? Available at https://www.mcgill.ca/newsroom/channels/news/lsd-future-anti-anxiety-pill-338481. Last accessed June 15, 2022.

71. Gasser P, Holstein D, Michel Y, et al. Safety and efficacy of lysergic acid diethylamide-assisted psychotherapy for anxiety associated with life-threatening diseases. J Nerv Ment Dis. 2014;202(7):513-520.

72. Gasser P, Kirchner K, Passie T. LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: a qualitative study of acute and sustained subjective effects. J Psychopharmacol. 2015;29(1):57-68.

73. Bruhn JG, De Smet PAGM, El-Seedi HR, Beck O. Mescaline use for 5700 years. Lancet. 2002;359(9320):1866.

74. Uthaug MV, Davis AK, Haas TF, et al. The epidemiology of mescaline use: pattern of use, motivations for consumption, and perceived consequences, benefits, and acute and enduring subjective effects. J Psychopharmacol. 2022;36(3):309-320.

75. Agin-Liebes G, Haas TF, Lancelotta R, Uthaug MV, Ramaekers JG, David AK. Naturalistic use of mescaline is associated with self-reported psychiatric improvements and enduring positive life changes. ACS Pharmacol Transl Sci. 2021;4(2):543-552.

76. Whizar-Lugo VM, Heredia-Mota C, Camacho A. Back to the future: ketamine and nitrous oxide in major refractory depression.J Anesth Crit Care. 2017;9(3):1-5.

77. Gillman MA. Mini-review: a brief history of nitrous oxide (N2O) use in neuropsychiatry. Curr Drug Res Rev. 2019;11(1):12-20.

78. Silverman M, Hexem J. Nitrous oxide/oxygen sedation and the single-dose sedative. Inside Dentistry. 2011;42-54.

79. Quach DF, de Leon VC, Conway CR. Nitrous oxide: an emerging novel treatment for treatment-resistant depression. J Neurol Sci. 2022;434:120092.

80. Nagele P, Duma A, Kopec M, et al. Nitrous oxide for treatment-resistant major depression: a proof-of-concept trial. Biol Psychiatry. 2015;78(1):10-18.

81. Dryden J. Press Release: Laughing Gas Relieves Symptoms in People with Treatment-Resistant Depression. Available at https://medicine.wustl.edu/news/laughing-gas-relieves-symptoms-in-people-with-treatment-resistant-depression. Last accessed June 15, 2022.

82. Nagele P, Palanca BJ, Gott B, et al. A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression. Sci Transl Med. 2021;13(597):eabe1376.

83. Palhano-Fontes F, Barreto D, Onias H, et al. Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial. Psychol Med. 2019;49(4):655-663.

84. Osório Fde L, Sanches RF, Macedo LR, et al. Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report. Braz J Psychiatry. 2015;37(1):13-20.

85. Barker SA. Administration of N,N-dimethyltryptamine (DMT) in psychedelic therapeutics and research and the study of endogenous DMT. Psychopharmacology (Berl). 2022;239(6):1749-1763.

86. Romero S. Demand for This Toad's Psychedelic Toxin Is Booming. Some Warn That's Bad for the Toad. Available at https://www.nytimes.com/2022/03/20/us/toad-venom-psychedelic.html#:~:text=Toxin%20Is%20Booming.-,Some%20Warn%20That%27s%20Bad%20for%20the%20Toad.,at%20risk%20of%20population%20collapse. Last accessed June 15, 2022.

87. U.S. Food and Drug Administration. FDA Approves New Nasal Spray Medication for Treatment-Resistant Depression; Available Only at a Certified Doctor's Office or Clinic. Available at https://www.fda.gov/news-events/press-announcements/fda-approves-new-nasal-spray-medication-treatment-resistant-depression-available-only-certified. Last accessed June 21, 2022.

88. National Center for PTSD. How Common Is PTSD in Adults? Available at https://www.ptsd.va.gov/understand/common/common_adults.asp. Last accessed June 15, 2022.

89. Liriano F, Hatten C, Schwartz TL. Ketamine as treatment for post-traumatic stress disorder: a review. Drugs Context. 2019;8:212305.

90. Jerome L, Feduccia AA, Wang JB, et al. Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials. Psychopharmacology (Berl). 2020;237(8):2485-2497.

91. Johnson MW, Garcia-Romeu A, Cosimano MP, Griffiths RR. Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. J Psychopharmacol. 2014;28(11):983-992.

92. Johnson MW, Garcia-Romeu A, Griffiths RR. Long-term follow-up of psilocybin-facilitated smoking cessation. Am J Drug Alcohol Abuse. 2017;43(1):55-60.

93. Krupitsky EM, Burakov AM, Dunaevsky IV, Romanova TN, Slavina TY, Grinenko AY. Single versus repeated sessions of ketamine-assisted psychotherapy for people with heroin dependence. J Psychoactive Drugs. 2007;39(1):13-19.

94. Agrawal M. Psychedelics May Ease Cancer Patients' Depression, Anxiety. Available at https://www.washingtonpost.com/health/2022/04/02/cancer-psychedelics-psilocybin-anxiety-depression/. Last accessed June 15, 2022.

95. Griffiths RR, Johnson MW, Carducci MA, et al. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: a randomized double-blind trial. J Psychopharmacol. 2016;30(12):1181-1197.

96. Moreno FA, Wiegand CB, Taitano EK, Delgado PL. Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder. J Clin Psychiatry. 2006;67(11):1735-1740.

97. Martinotti G, Chiappini S, Pettorruso M, et al. Therapeutic potentials of ketamine and esketamine in obsessive-compulsive disorder (OCD), substance use disorders (SUD) and eating disorders (ED): a review of the current literature. Brain Sci. 2021;11(7):856.

98. Rodriguez CI, Kegeles LS, Levinson A, et al. Randomized controlled crossover trial of ketamine in obsessive-compulsive disorder: proof-of-concept. Neuropsychopharmacology. 2013;38(12):2475-2483.

99. Bloch MH, Wasylink S, Landeros-Weisenberger A, et al. Effects of ketamine in treatment-refractory obsessive-compulsive disorder. Biol Psychiatry. 2012;72(11):964-970.

100. Danforth AL, Grob CS, Struble C, et al. Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study. Psychopharmacology (Berl). 2018;235(11):3137-3148.

101. National Institute of Mental Health. Social Anxiety Disorder. Available at https://www.nimh.nih.gov/health/statistics/social-anxiety-disorder. Last accessed June 15, 2022.

102. Mills IH, Park GR, Manara AR, Merriman RJ. Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions. QJM. 1998;91(7):493-503.

103. Scolnick B, Zupec-Kania B, Calabrese L, Aoki C, Hildebrandt T. Remission from chronic anorexia nervosa with ketogenic diet and ketamine: case report. Front Psychiatry. 2020;11:763.

104. International Headache Society. The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;33(9):629-808.

105. Sewell RA, Halpern JH, Pope HG Jr. Response of cluster headache to psilocybin and LSD. Neurology. 2006;66(12):1920-1922.

106. U.S. National Library of Medicine. Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache (LCH). Available at https://clinicaltrials.gov/ct2/show/NCT03781128. Last accessed June 20, 2022.

107. Pomeroy JL, Marmura MJ, Nahas SJ, Viscusi ER. Ketamine infusions for treatment refractory headache. Headache. 2017;57(2):276-282.

108. Nikayin S, Taylor JJ, Ostroff RB. Advanced training in interventional psychiatry. J Neurol Sci. 2022;434:120093.

109. Gazdag G, Ungvari GS. Electroconvulsive therapy: 80 years old and still going strong. World J Psychiatry. 2019;9(1)1-6.

110. Salik I, Marwaha R. Electroconvulsive Therapy. Available at https://www.ncbi.nlm.nih.gov/books/NBK538266. Last accessed June 15, 2022.

111. Mental Health America. Electroconvulsive Therapy (ECT). Available at https://www.mhanational.org/ect. Last accessed June 15, 2022.

112. Espinoza RT, Kellner CH. Electroconvulsive therapy. N Engl J Med. 2022;386(7):667-672.

113. Subramanian S, Lopez R, Zorumski CF, Cristancho Pilar. Electroconvulsive therapy in treatment resistant depression. J Neurol Sci. 2022;434:120095.

114. Mohn C, Rund BR. Maintained improvement of neurocognitive function in major depressive disorders 6 months after ECT. Front Psychiatry. 2016;7:200.

115. Göterfelt L, Ekman CJ, Hammar A, et al. The incidence of dental fracturing in electroconvulsive therapy in Sweden. J ECT. 2020;36(3):168-171.

116. Wilkinson ST, Kitay BM, Harper A, et al. Barriers to the implementation of electroconvulsive therapy (ECT): results from a nationwide survey of ECT practitioners. Psychiatr Serv. 2021;72(7):752-757.

117. Wilkinson ST, Agbese E, Leslie DL, Rosenheck RA. Identifying recipients of electroconvulsive therapy: data from privately insured Americans. Psychiatr Serv. 2018;69(5):542-548.

118. U.S. Food and Drug Administration. FDA Permits Marketing of Transcranial Magnetic Stimulation for Treatment of Obsessive Compulsive Disorder. Available at https://www.fda.gov/news-events/press-announcements/fda-permits-marketing-transcranial-magnetic-stimulation-treatment-obsessive-compulsive-disorder. Last accessed June 21, 2022.

119. Mahoney JJ III, Hanlon CA, Marshalek PJ, Rezai AR, Krinke L. Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: review of modalities and implications for treatment. J Neurol Sci. 2020;418:117149.

120. Lefaucheur JP, Aleman A, Baeken C, et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): an update (2014–2018). Clin Neurophysiol. 2020;131(2):474-528.

121. Davila MC, Ely B, Manzardo AM. Repetitive transcranial magnetic stimulation (rTMS) using different TMS instruments for major depressive disorder at a suburban tertiary clinic. Ment Illn. 2019;11(1):7947.

122. Belgers M, Van Eijndhoven P, Markus W, Schene AH, Schellekens A. rTMS reduces craving and alcohol use in patients with alcohol use disorder: results of a randomized, sham-controlled clinical trial. J Clin Med. 2022;11(4):951.

123. LaFee S. Major Contract Fuels Three-University Study of TMS for Treating Depression. Available at https://health.ucsd.edu/news/releases/Pages/2022-02-22-major-contract-fuels-three-university-study-of-tms-for-treating-depression.aspx. Last accessed June 15, 2022.

124. Hageman M. This New Treatment Cured Depression in 80 Percent of People, Study Says. Available at https://bestlifeonline.com/depression-treatment-news. Last accessed June 15, 2022.

125. Cleveland Clinic. Vagus Nerve. Available at https://my.clevelandclinic.org/health/body/22279-vagus-nerve. Last accessed June 15, 2022.

126. Thompson SL, O'Leary GH, Austelle CW, et al. A review of parameter settings for invasive and non-invasive vagus nerve stimulation (VNS) applied in neurological and psychiatric disorders. Front Neurosci. 2021;15:709436.

127. U.S. Food and Drug Administration. FDA Approves First-of-Its-Kind Stroke Rehabilitation System. Available at https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-stroke-rehabilitation-system. Last accessed June 21, 2022.

128. Desbeaumes Jodoin V, Richer F, Miron JP, Fournier-Gosselin MP, Lespérance P. Long-term sustained cognitive benefits of vagus nerve stimulation in refractory depression. J ECT. 2018;34(4):283-290.

129. Krauss JK, Lipsman N, Aziz T, et al. Technology of deep brain stimulation: current status and future directions. Nat Rev Neurol. 2021;17(2):75-87.

130. Pool JL. Psychosurgery in older people. J Am Geriatr Soc. 1954;2(7):456-466.

131. Youssef NA, Dela Cruz SAMF, Riva-Posse P, Patel RS. Characteristics of patients who had deep brain stimulation for treatment-resistant depression from among 116,890 inpatients with major depressive disorder. Ann Clin Psychiatry. 2021;33(4):251-257.

132. Kahn L, Sutton B, Winston HR, Abosch A, Thompson JA, Davis RA. Deep brain stimulation for obsessive-compulsive disorder: real world experience post-FDA-humanitarian use device approval. Front Psychiatry. 2021;12:568932.

133. Zhang C, Zhang Y, Luo H, et al. Bilateral habenula deep brain stimulation for treatment-resistant depression: clinical findings and electrophysiological features. Transl Psychiatry. 2022;12(1):52.

134. Sheth SA, Bijanki KR, Metzger B, et al. Deep brain stimulation for depression informed by intracranial recordings. Biol Psychiatry. 2021; [Epub ahead of print].

135. U.S. Drug Enforcement Administration. Press Release: DEA Issues Public Safety Alert on Sharp Increase in Fake Prescription Pills Containing Fentanyl and Meth. Available at https://www.dea.gov/press-releases/2021/09/27/dea-issues-public-safety-alert. Last accessed June 15, 2022.

136. Correa da Costa S, Oesterle T, Rummans TA, Richelson E, Gold M. Psychedelic drugs for psychiatric disorders. Journal of the Neurological Sciences. 2022;440:120332.

137. Lee YK, Gold MS, Fuehrlein BS. Looking beyond the opioid receptor: a desperate need for new treatments for opioid use disorder. J Neurol Sci. 2022;432:120094.

138. Gerber K, García Flores I, Ruiz AC, Ali I, Ginsberg NL, Schenberg EE. Ethical concerns about psilocybin intellectual property. ACS Pharmacol Transl Sci. 2021;4(2):573-577.